Guidelines Review Committee
Latest WHO guidelines approved by the Guidelines Review Committee
All →WHO handbook for guideline development
This handbook provides detailed instructions for guideline developers on the following topics:
- application of high-quality methodology for guideline development using systematic search strategies, synthesis and quality assessment of the best available evidence to support the recommendations;
- appropriate collection and management of experts’ declared conflict of interest;
- expert group composition including content experts, methodologists, target users, policy makers, with gender and geographical balance;
- instructions for the management of group process to achieve consensus among experts;
- standards for a transparent decision-making process, taking into consideration potential harms and benefits, end-users' values and preferences;
- developing plans for implementing and adapting guidelines; and
- minimum standards for reporting.
For additional, online, chapters click on Read More on the right-hand side.
Handbook update under development 2025.
The BIGG-REC database is a comprehensive and searchable repository of all WHO/PAHO evidence informed recommendations formulated using GRADE.
The database is searchable according to questions of interest, based on the key components of the question (PICO - population, interventions, comparators, and outcomes).
The aim of BIGG Rec is to help local, provincial, regional and jurisdictional decision-makers and health care workers adapt and adopt evidence-based recommendations.
This platform will feed on continued input from guideline developers which we encourage and users and, thus, its functions will continue to improve and it will be updated regularly to maintain relevance.